Enhanced Speed with a 2 kHz (kiloHertz) proprietary smartbeam-II solid-state laser
(modified Nd:YAG laser) 355 nm and electronics for high throughput applications
including MALDI Imaging, and high-throughput microbiology ID
• Laser focus diameters down to 10 µm for high spatial resolution imaging without
pixel overlap.
• TOF-analyzer for linear and reflectron mode, MS/MS capability TOF-analyzer for
both positive and negative ion mode
• Reflectron resolution ≥ 26000 FWHM ( Somatostatin 28; m/z 3147.47 Da), mass
accuracy < 10ppm (external calibration)
• Linear resolution ≥1,100 for Cytochrome C (m/z 12,361) and ≥ 600 for Protein
A (m/z 44,613) . linear mass accuracy for Cytochrome C <100 ppm (external
calibration)
• Mass accuracy (protein mixture): with external calibration: better than 100 ppm
with internal calibration: better than 90 ppm
• MS sensitivity: 500 fmol BSA (m/z 66,000). S/N ≥ 100
• Expanded mass range capabilities to handle intact proteins and molecules such
as large protein and polymers.
LIFT™ – the latest TOF/TOF technology to enable the use of various MS/MS
techniques, including LID and high-energy CID
• Minimized maintenance with IR laser-based self-cleaning MALDI Perpetual™ Ion
Source, which improves system up-time and utility.
• Optimized Software packages for numerous applications e.g. Protein-, Peptide-,
Polymer-Analyses, and MALDI Imaging, clinical research methods and the
MALDI Biotyper workflow.
Autoflex speed™ MALDI TOF/TOF
Matrix-Assisted Laser Desorption/Ionization(MALDI) stands as one of the most powerful
techniques invented for investigating:
1. Biopolymers (such as peptides, proteins, glycansand oligonucleotides)
2. Synthetic polymers and organic molecules (>500 Da), especially in mixtures and crude samples
3. MALDI Imaging. Distribution of proteins,lipid, smallmolecules and etc. in tissue sections.
Results are shown as color coded intensity plots and can be overlaid to an image of the
investigated sample
5. TLC MALDI. Measurements directly from a thin layerchromatography (TLC)
6. Microorganism and Fungi identification and classification
7. Detailed sample characterization by MS/MS.
8.Top down proteomics.
Location: Building No. 51, Room No. 232
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