The next generation of high-resolution mass-spectrometers that can be used for Data Independent Analysis (DIA) and Parallel Reaction Monitoring (PRM) with a higher scan speed and faster polarity switch. The MS is equipped with an ESI source that provides soft ionization of the molecules. Resolving power is up to 240,000 Full Width at Half Maximum (FWHM). Mass Range for Full Scans is m/z 40–3000 (Scan range: last mass ≤ 15 × first mass), and mass accuracy is 1ppm.