The IKI Electron Microscopy Unit provides expertise and resources for solving macromolecular structures. Our new high-end transmission electron microscope enables high-resolution structure determination of macromolecular complexes. We provide access to Thermo-Fisher Glacios, with the state-of-the-art Falcon 4i direct detection camera coupled to a Selectris X energy filter for high-contrast micrographs. All the required computational support necessary for single-particle analysis is also available for our users. Higher-order structure determination is enabled by tomographic reconstructions using the same setup. Grids sample preparation expertise and equipment (Leica EM GP) are also available.

Our equipment is available for use of BGU faculty, other universities faculty, and industry upon application. To apply for microscope time, a detailed work plan, and prices please contact Dr. Ran Zalk at ranz@bgu.ac.il.

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“High-resolution Cryo-EM structure determination”